Read e-book online Advances in Immunology, Vol. 96 PDF

By Frederick W. Alt

ISBN-10: 0123737095

ISBN-13: 9780123737090

Advances in Immunology , a fashioned and hugely revered ebook, provides present advancements in addition to accomplished studies in immunology. Articles tackle the wide variety of issues that contain immunology, together with molecular and mobile activation mechanisms, phylogeny and molecular evolution, and scientific modalities. Edited and authored by means of the major scientists within the box, each one quantity offers up to date info and instructions for destiny learn.

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19, 218–228. , He, T. , and Ransohoff, R. M. (2006a). Severe disease, unaltered leukocyte migration, and reduced IFN-gamma production in CXCR3À/À mice with experimental autoimmune encephalomyelitis. J. Immunol. 176, 4399–4409. , and Issazadeh-Navikas, S. (2006b). Neuron-mediated generation of regulatory T cells from encephalitogenic T cells suppresses EAE. Nat. Med. 12, 518–525. Lucchinetti, C. , Mandler, R. , Ransohoff, R. , Parisi, J. , and Lassmann, H. (2002). A role for humoral mechanisms in the pathogenesis of Devic’s neuromyelitis optica.

Cell Immunol. 164, 295–305. , Hartung, H. , and Jung, S. (2001). Suppression of experimental autoimmune neuritis by leflunomide. Brain 124, 1791–1802. , Nussenzweig, M. , and von Boehmer, H. (2005). Inducing and expanding regulatory T cell populations by foreign antigen. Nat. Immunol. 6, 1219–1227. , and Holz, A. (2006). Spontaneous opticospinal encephalomyelitis in a double-transgenic mouse model of autoimmune T cell/B cell cooperation. J. Clin. Invest. 116, 2385–2392. Kuchroo, V. , Martin, C.

Daclizumab is currently being investigated in a Phase III clinical trial. 2. , 2005). ) that finally lead to cholesterol synthesis. This pathway is a source of hydrophobic molecules important for a wide range of inter- and intracellular functions involving hormonal communication, protein synthesis, electron transport, protein lipid modification for membrane anchoring and intracellular signaling (via isoprenoids), and cell membrane maintenance (via cholesterol). Previous studies demonstrating the anti-inflammatory nature of statins revealed the possible benefits of employing these agents for the treatment of inflammatory autoimmune disorders such as MS or rheumatoid arthritis (RA).

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Advances in Immunology, Vol. 96 by Frederick W. Alt

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